Human T cell lifespan (P1284)

摘要: In humans, the lifespan and turnover of T cells have been debated for almost half a century. Until now, analysis lymphocyte primarily approached through short term labelling studies nucleotide analogue incorporation. While much has gained from these endeavours, there is still considerable debate about live different subsets it apparent that neither approach alone can give necessary information to reach conclusive result. Taking advantage decreasing concentration 14C in atmosphere since cold war, we retrospectively assessed birth date cell populations blood healthy adult humans.