Validation of a modified clinical risk score to predict cancer‐specific survival for stage II colon cancer
作者： Raymond Oliphant , Paul G. Horgan , David S. Morrison , Donald C. McMillan ,
DOI: 10.1002/CAM4.352
关键词: Colorectal cancer 、 Multivariate analysis 、 Clinical risk factor 、 Internal medicine 、 Surgery 、 Clinical audit 、 Stage ii colon cancer 、 Confidence interval 、 Disease 、 Hazard ratio 、 Medicine
摘要: Many patients with stage II colon cancer will die of their disease despite curative surgery. Therefore, identification at high risk poor outcome after surgery for is desirable. This study aims to validate a clinical score predict cancer-specific survival in undergoing cancer. Patients 16 hospitals the West Scotland between 2001 and 2004 were identified from prospectively maintained regional audit database. Overall rates up 5 years calculated. A total 871 included. At 5 years, was 81.9% overall 65.6%. On multivariate analysis, age ≥75 years (hazard ratio (HR) 2.11, 95% confidence intervals (CI) 1.57–2.85; P<0.001) emergency presentation (HR 1.97, CI 1.43–2.70; independently associated survival. Age mode HRs added form 0–2. The cumulative 0 88.7%, 1 78.2% 2 65.9%. These results modified simple combination these two universally documented factors provides solid foundation examination impact additional clinicopathological treatment on
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