The associations of residential greenness with fetal growth in utero and birth weight: A birth cohort study in Beijing, China

作者: Lizi Lin , Qin Li , Jie Yang , Na Han , Gongbo Chen

DOI: 10.1016/J.ENVINT.2020.105793

关键词: Birth weightIn uteroSmall for gestational ageDemographyMedicineFetusGeneralized estimating equationPregnancyConfidence intervalLow birth weight

摘要: Background: Although studies have examined the association between residential greenness and birth weight, there is no evidence regarding fetal growth in utero. We aimed to investigate associations of with both utero weight. Methods: A cohort (2014–2017) 18,665 singleton pregnancies was established Tongzhou Maternal Child hospital Beijing, China. Residential matched maternal address estimated from remote satellite data using normalized difference vegetation index 200 m 500 buffers (NDVI-200 NDVI-500). Fetal parameters including weight (EFW), abdominal circumference (AC), head (HC) femur length (FL) were assessed by ultrasound measurements during pregnancy. standardized as gestational-age- gender-adjusted Z-score undergrowth defined < −1.88. Birth Z-score, low (LBW) small for gestational age (SGA) outcomes. Generalized estimating equations autoregressive working correlation structure generalized linear regression used examine quantitative categorized Results: found an increase EFW [0.054, 95% confidence interval (CI): 0.020–0.087], AC (0.045, 95%CI: 0.011–0.080) HC (0.054, 0.020–0.089) associated above NDVI-500 median compared less than equal median. Stratified analyses indicated that might be stronger women exposed lower levels particles aerodynamic diameters ≤2.5 µm. No NDVI-250 didn't observe significant NDVI LBW SGA. Conclusions: This study identified a positive utero, but we its measures. Our results suggest building sufficient green infrastructure potentially promote early life health.

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