Efficacy of debridement and wound cleansing with 2% hydrogen peroxide on graft take in the chronic-colonized burn wounds; a randomized controlled clinical trial.

摘要: Abstract Background Severe burns are associated with dramatic outcomes which potentially detrimental. Nowadays the standard treatment for deep partial thickness and full-thickness burn is early excision grafting, not always feasible this leads to chronicity microbial colonization of wounds. Interesting properties hydrogen peroxide 2% soaked gauze convinced us use it in management chronic Methods From January 2009 September 2011, a prospective clinical trial, 49 patients (98 limbs) chronic-colonized wounds both limbs were included study. Tissue cultures taken from all For right, after debridement granulation tissue washing 5 min followed by normal saline irrigation, grafting was done; skin performed conventional method left limb The success rate graft take compared between two groups, 21 days surgeon using formula:. Graft surface area ( cm 2 ) × 100 % Total grafted Results study group composed 98 mean age 26.44 ± 5.66 28.3 ± 7.23% TBSA. most common causes delayed admission poor compliance. (44.8%) Staphylococcus frequent isolate bacterial our patients. (59.2%) Mean 82.85% right limbs, 65.61% limbs; significantly different P Conclusions Our showed that, administration intraoperatively appears be safe increases Therefore, can recommended management.