Recent Advances: Molecular Mechanism of RNA Oxidation and Its Role in Various Diseases.
作者： Zhe Li , Xiatian Chen , Ziqian Liu , Wei Ye , Ling Li
关键词: DNA 、 Disease 、 RNA 、 Cell biology 、 Reactive oxygen species 、 Biology 、 Mechanism (biology) 、 DNA damage 、 Protein biosynthesis 、 Translation (biology)
摘要: Compared with the research on DNA damage, there are fewer studies RNA and damage mechanism remains mostly unknown. Recent have shown that is more vulnerable to than when cells exposed endogenous exogenous insults. injury may participate in a variety of disease occurrence development. not only has important catalytic functions other housekeeping functions, it also plays decisive role translation genetic information protein biosynthesis. Various kinds stressors, such as ultraviolet, reactive oxygen species nitrogen, can cause RNA. It involve development progression diseases. In this review, we focused relationship between well progress which great significance for pathogenesis, diagnosis, treatment related
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