Amplification Mechanisms in Platelet Activation

作者: F. De Clerck , D. De Chaffoy De Courcelles

DOI: 10.1007/978-94-009-1912-9_11

关键词: PlateletPlatelet activationHuman plateletAgonistChemistrySerotoninPharmacologyArterial thrombusPotency

摘要: Platelets, as they contribute to the formation of an hemostatic plug or arterial thrombus, are exposed a multitude agonists, acting with different strength in concert on same target cells amplify each other effects. Such amplification, rather then potency agonists singly, determines true impact so-called weak agonist serotonin platelet reactions pathology.

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