Prognostic impact and implications of extracapsular lymph node spread in Borrmann type IV gastric cancer

摘要: The purpose of this study was to evaluate the relationship between extracapsular lymph node spread (ECS) and clinicopathology its influence on prognosis in patients with Borrmann type IV gastric cancer. Between 2002 2014, clinical data were reviewed from 486 cancer who underwent curative resection. Of patients, metastasis found 456. ECS detected 213 (46.7%) metastasis. A positive significantly correlated N category, lymphatic/venous invasion, tumor location, TNM stage. For whole mean OS 34.7 months, 5-year rate 15.5%. node-negative 48%, for node-positive without 18.7%, 5.7% (P = 0.000). In a multivariate analysis, adjusted body mass index (BMI), stages, remained an independent prognostic factor. same category stage, those still had worse survival rate. Recurrent sites confirmed 367 patients. most frequent recurrent site peritoneum. There significant difference ECS+ (N 150) ECS- 142) 0.008). Our results suggested that value resection subgroup indicated long-term or stages. adverse factor peritoneal