Cost-effectiveness analysis of cervical cancer screening strategies based on the Papanicolaou smear test in Korea.

摘要: Background Despite the increasing number of screening examinations performed for cervical cancer utilizing Papanicolaou smear test (Pap test), few studies have examined whether this strategy is cost-effective in Korea. Objective This study was conducted to evaluate cost-effectiveness strategies incorporating Pap based on age at start and end as well interval. Materials methods We designed four alternative patient when started (20 or 30 years) discontinued (lifetime, 79 years). Each assessed intervals 1, 2, 3, 5 years. A Markov model developed determine 16 possible strategies, evaluated from a societal perspective. The main outcome measures were average lifetime cost, incremental quality-adjusted life-years (QALYs), ratio (ICER). Results Compared with various comprising younger starting age, discontinuation longer intervals, employing annual target years above most cost-effective, an ICER 21,012.98 dollars per QALY gained (with Korean threshold 30,000,000 KRW US$27,272). Conclusions found that beginning strategy. Considering potential economic advantages, more intense policies might be favorable among countries high rates relatively low costs.