The role of autopsy findings in multicenter treatment evaluations as exemplified by two aspirin trials.

摘要: In many treatment trials the aim is to prevent deaths from one type of disease. The cause death evaluation therefore utmost importance. A high autopsy rate required, even as regards sudden that cannot routinely be referred ischemic heart Autopsies are also necessary for studying non-lethal and lethal side effects involved drug. Even in best cases post-mortem far 100% correctness not ensured. If has prevented studied, this gain must outweighed by increases other causes death, result considered reliably positive