Control of Translation Initiation in Hamnalian Cells
DOI: 10.1007/978-1-4613-0641-2_13
关键词: Messenger RNA 、 Translational efficiency 、 Cytoplasm 、 Protein biosynthesis 、 Cell biology 、 Chemistry 、 MRNA transport 、 Gene expression 、 Elongation 、 Eukaryotic translation
摘要: Protein synthesis is an important regulatory step in gene expression. The rate of protein controlled by the amount mRNA available to translational machinery and efficiency mRNA. former involves transcription, processing, transport cytoplasm, half-life Translational determined structure, level activity machinery, factors that influence initiation elongation rates. Most control thought be exerted at synthesis. Initiation primarily structure 5’ end translation factors. Factors which may essentially all cellular mRNAs or specific.
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