Chromatin accessibility of circulating CD8+ T cells predicts treatment response to PD-1 blockade in patients with gastric cancer.
作者： Jiyeob Choi , Seung Tae Kim , Sangjib Kim , Ji Hyun Sim , Jeeyun Lee
DOI: 10.1038/S41467-021-21299-W
关键词: Pembrolizumab 、 Chromatin 、 Immunotherapy 、 Epigenetics 、 Cancer 、 Cancer research 、 CD8 、 Cell growth 、 Cytotoxic T cell 、 Medicine
摘要: Although tumor genomic profiling has identified small subsets of gastric cancer (GC) patients with clinical benefit from anti-PD-1 treatment, not all responses can be explained by tumor …
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