Cellular mechanisms underlying prostaglandin-induced transient cAMP signals near the plasma membrane of HEK-293 cells.
作者： Thomas C. Rich , Wenkuan Xin , Celine Mehats , Kathryn A. Hassell , Leslie A. Piggott
DOI: 10.1152/AJPCELL.00121.2006
关键词: Phosphodiesterase 、 Signal transduction 、 Prostaglandin 、 Prostaglandin E1 、 Cell biology 、 HEK 293 cells 、 Protein kinase A 、 Ion channel 、 Biology 、 Biochemistry 、 G protein
摘要: We have previously used cyclic nucleotide-gated (CNG) channels as sensors to measure cAMP signals in human embryonic kidney (HEK)-293 cells. found that prostaglandin E1 (PGE1) triggered transien...
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