In Vitro Coculture Models to Study Vessel Formation and Function

作者: Karen K. Hirschi , Patricia A. D’Amore

DOI: 10.1007/978-1-4612-4156-0_10

关键词: Cell biologyFunction (biology)In vitroBlood vesselAngioblastMesodermOrgan systemChemistryMural cellEmbryo

摘要: The vasculature is one of the first organ systems to develop and provides a means distributing nutrients oxygen, as well removing waste products in developing embryo. Hence, blood vessel formation vital establishment maintenance all tissues body. primitive vascular network formed almost entirely from mesoderm during vasculo genesis, which begins with differentiation angioblasts into tubelike endothelial structures (Doetschman et al., 1985; Coffin Poole, 1988; Noden, 1989).

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