Chemistry and Physiology of the Transferrins

摘要: Iron in aqueous solution, near neutral pH and atmospheric oxygen tension, seeks the ferric state as its thermodynamically stable form. Because of insolubility hydroxide, however, organisms at all levels biological development have been obliged to elaborate specific iron-binding molecules maintain this essential metal soluble, bioavailable In vertebrate world, function iron transport is given transferrins, a class two-sited proteins distinguished by interdependence anion metalion binding. The mechanisms release whether nature protein serves biologic function, are still unsettled questions biochemistry metabolism.