Transdermal therapeutic system for administering fentanyl or an analogue thereof
作者： Ingo Teutsch , Nouha Salman , Bjoern Schurad
DOI:
关键词: Medicine 、 Anesthesia 、 Pharmacology 、 Fentanyl 、 Transdermal
摘要: Disclosed is a transdermal therapeutic system for administering an active substance through the skin, comprising: a) backing; b) reservoir that located on backing and comprises b1) first layer containing substance, at least one gelatinizing agent, emollient, polyisobutylene, b2) second polyisobutylene different from other polyisobutylene. At contains undissolved in form of particles, said being fentanyl or analogue.
google.it 参考文章(15)
Eun S Lee, Victor Goetz, Robert M Gale, Su Ii Yum, Lina T Taskovich, Transdermal administration of fentanyl and device therefor ,(1984)
Naruhito Higo, Takeshi Ito, Tetsuro Tateishi, Transdermal patch for external use comprising fentanyl ,(2003)
Russell D. Beste, Russell Adam Baird, Brad L. Barnett, Process for the continuous manufacture of a polyisobutylene based transdermal patch ,(2010)
Hitoshi Akemi, Yoshifumi Hosaka, Hidetoshi Kuroda, Kensuke Matsuoka, Masato Nishimura, Takateru Muraoka, Yuji Saeki, Mitsuhiko Hori, Kazuhisa Ninomiya, adhesive preparation containing fentanyl. ,(2005)
Su Il Yum, Felix Theeuwes, Transdermal delivery systems ,(2005)
Jane Stepic, Subramanian S. Venkatraman, Robert M. Gale, Osdol William W. Van, Shaoling Li, Transdermal patch for administering fentanyl ,(2002)
Andrea Breuer, Christoph Fiehn, Hans-Hermann Schrenk, Eva Frei, Paul Kremer, Albumin conjugates containing a glucuronic linker ,(2004)
Jie Zhang, Improved transdermal drug patch ,(2001)
Ingo Teutsch, Nouha Salman, Björn Schurad, Transdermal therapeutic system for application of fentanyl or an analogue material thereof ,(2009)