Total Atherosclerosis Burden of Baroreceptor-Resident Arteries Independently Predicts Blood Pressure Dipping in Patients With Ischemic Stroke

摘要: Nighttime blood pressure (BP) generally dips by 10% to 20% of the daytime values, and abnormal BP dipping may affect vascular health independently level. The regulation involves arterial baroreflex, whose receptors mainly reside in carotid sinuses aortic arch. Atherosclerosis these baroreceptor-resident arteries (BRAs) is frequent among patients with ischemic stroke (IS) might impair their BP-regulating capacity. We aimed examine associations between atherosclerosis BRA IS. ratio was measured 24-hour ambulatory monitoring on sixth day after With computed tomography angiography, conditions 10 segments arch were scored summed as total burden BRA. Among 245 IS, 78.0% had AS negatively correlated systolic (r=-0.331; P<0.001) diastolic (r=-0.225; P<0.001). After adjusting for age, sex, risk factors, means, cervical intracranial scores, negative correlations still existed (adjusted β, -0.259 [95% CI, -0.416 -0.102] adjusted -0.178 -0.346 -0.010], respectively). In conclusion, higher indicative more blunted be important predicting managing