Virological, serological and epidemiological study of 255 consecutive cases of genital herpes in a sexually transmitted disease clinic of Paris (France): a prospective study

摘要: Some studies (mostly retrospective) have pointed to an increasing frequency (up 60%) of herpes simplex virus type 1 (HSV-1) in genital (GH), but they were biased towards severe or atypical cases. We wished evaluate the HSV-1 patients attending our clinic for both first and recurrent episodes GH.All (men women) with lesions compatible GH included a prospective study between May 1999 April 2002. For all standardized questionnaire, clinical examination, MRC5 culture (Dade Behring), polymerase chain reaction (PCR)-herpes consensus (Argene Biosoft) case negative type-specific serology HSV-2 (Elisa Eurobio) obtained. Predictive factors associated studied by uni- multivariable analyses.In all, 255 had positive (n = 216) PCR 39). A total 248 typable (148 men 100 women). Median age was 33 (27–43); 20% anal...