Extracorporeal circulation (ECMO) in neonatal respiratory failure.

摘要: Sixteen moribund newborn infants with respiratory failure were treated extracorporeal membrane oxygenation (ECMO) for 1 to 8 days. Cannulation via the right jugular vein and carotid artery was used establish venoarterial-cardiopulmonary bypass. High flow (80 percent of cardiac output) allowed decreasing FIO2 airway pressure. Diagnoses results as follows: distress syndrome, four patients (two improved, one survived); meconium aspiration eight (four three persistent fetal circulation (some diaphragmatic hernia), (three two survived). Intracranial bleeding occurred in 43 percent, accounting most deaths. In a parallel series 21 conventional ventilator therapy, mortality rate 90 intracranial 57 percent. ECMO provided life support gains time failure. high risk infants, survival is higher lower than optimal management.