Hypoxia and the pulmonary circulation.

摘要: It is a singularly interesting fact that sustained hypoxia exerts diametrically opposite effects on the systemic and pulmonary circulations. In general, has relaxing effect smooth muscle it brings about vasodilatation in circulation. Native highlanders sojourners at high altitude for many years exhibit fall blood pressure (Heath Williams, 1977). sharp contrast to this, most powerful vasoconstrictor known, giving rise increased vascular resistance hence arterial hypertension. Since original demonstration of this cat by von Euler Liljestrand (1946) there been an impressive accumulation supporting experimental evidence from variety animal species man recently we have extensively reviewed these data (Harris Heath,