作者: Jodi M. Lestner , P. Brian Smith , Michael Cohen-Wolkowiez , Daniel K. Benjamin , William W. Hope
DOI: 10.1111/BCP.12025
关键词: Perspective (graphical) 、 Antifungal 、 Medicine 、 Pharmacokinetics 、 Intensive care medicine 、 Pharmacodynamics
摘要: Invasive fungal infections, although relatively rare, are life-threatening diseases in premature infants and immunocompromised children. While many advances have been made antifungal therapeutics the last two decades, knowledge of pharmacokinetics pharmacodynamics agents for children remains incomplete. This review summarizes pharmacology clinical utility currently available discusses opportunities challenges future research.