Candida colonization and systemic infection in neutropenic patients. A retrospective study
作者： Pietro Martino , Corrado Girmenia , Mario Venditti , Alessandra Micozzi , Stefania Santilli
DOI: 10.1002/1097-0142(19891115)64:10<2030::AID-CNCR2820641011>3.0.CO;2-2
关键词: Surgery 、 Complication 、 Colonization 、 Mycosis 、 Medicine 、 Systemic candidiasis 、 Internal medicine 、 Amphotericin B 、 Antibiotics 、 Neutropenia 、 Retrospective cohort study 、 Cancer research 、 Oncology
摘要: The results of surveillance cultures in 424 neutropenic patients with hematologic malignancies were analyzed to evaluate the relationship between colonization and infection by Candida species. Eighteen (32%) 56 multiple noncontiguous colonized sites developed proven (13 cases) or probable (five systemic candidiasis, versus two candidiasis (1.2%) 170 one site (P less than 0.00000001), patient (0.5%) 198 without any evidence 0.00000001). Twenty-two who a febrile episode resistant antibiotics treated empiric amphotericin B. Nine 11 given B within day 6 survived three receiving antifungal therapy after = 0.014). above data seem justify further prospective studies on as indication early patients.
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