Competition, Saturation, and Inhibition-Ionic Interactions Shown by Membrane Ionic Currents in Nerve, Muscle, and Bilayer Systems*

作者: Robert J. French , William J. Adelman

DOI: 10.1016/S0070-2161(08)60197-5

关键词: BilayerMembraneNanotechnologySaturation (chemistry)IonPhase (matter)Ionic bondingBiophysicsLipid bilayerTransmembrane proteinChemistry

摘要: Publisher Summary This chapter focuses on the passive systems responsible for excitability in nerve and muscle membranes analogies that may be drawn with some lipid bilayer systems. It mentions selected papers serve to outline chronological accumulation of experimental evidence documenting ionic interaction effects transmembrane currents. Various nonlipid components added enhance their ability conduct an current under influence a electric field. Structural functional properties are consistent idea these substances form pores or channels through membrane lipid, whereas others act as carriers, complexing ions then diffusing across phase. A number theoretical approaches competition saturation have been applied success data from bilayer, nerve, preparations. These analyses almost invariably based reaction rate theory. The compares details discusses restrictions models demanded by cxperimental various

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