Gastrointestinal Tract Metabolism in the Fetus and Neonate

作者: Robert E. Kimura

DOI: 10.1007/978-1-4612-1642-1_30

关键词: MetabolismOxidative phosphorylationKetogenesisSmall intestineChemistryKetone bodiesFatty acidCarbohydrateInternal medicineCitric acid cycleEndocrinology

摘要: The transition from suckling to postweaned conditions in the developing rat provides a natural model for examining effect of changes energy requirements and oxidative substrates on intestinal metabolism. In small intestine, are not only delivered by blood, but immediately available absorption luminal substrates. Changes diet that occur during weaning have been shown alter intracellular fatty acid concentrations mucosal cells. pup consists high percentage lipid (approximately 70% total caloric content).1 During suckling, concentration free acids serum is markedly elevated as compared with adult concentration2 esterified jejunal cells increased.3 pup’s one predominantly carbohydrate. Furthermore, decrease those found adult. Finally, an increase liver ketogenesis period results ketone concentrations. These abrupt bodies provide perturbation can

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