Anterior knee pain in younger adults as a precursor to subsequent patellofemoral osteoarthritis: a systematic review

摘要: Patellofemoral osteoarthritis (PFOA) is a common form of knee OA in middle and older age, but its relation to PF disorders symptoms earlier life unclear. Our aim was conduct systematic review investigate the strength evidence for an association between anterior pain (AKP) younger adults subsequent PFOA. The search strategy included electronic databases (Pubmed, EMBASE, AMED, CINAHL, Cochrane, PEDro, SportDiscus: inception December 2009), reference lists potentially eligible studies selected reviews. Full text articles any language, - identified via English titles abstracts, were if they retrospective or prospective design contained quantitative data regarding structural changes indicative PFOA, incident original idiopathic AKP. Eligibility criteria applied titles, abstracts full-texts by two independent reviewers. Data extraction study location, design, date, sampling procedure, sample characteristics, AKP/PFOA definitions, follow-up duration rate, main findings. Foreign language translated into prior examination. Seven satisfied eligibility (5 English, 2 German). Only one case-control directly investigated link PFOA AKP, providing level 3b favour (OR 4.4; 95%CI 1.8, 10.6). Rough estimates annual risk from remaining six small, uncontrolled, observational (mean range: 5.7 23 years) ranged 0% 3.4%. This not primary these studies, limitations methodology mean this should be interpreted with caution. There paucity high-quality reporting AKP Further, well-designed cohort may able fill gap.