作者: Harold L. Atkins
DOI: 10.1016/S0001-2998(79)80044-6
关键词: Cancer research 、 Intracellular 、 Osteosarcoma 、 Liposome 、 Medicine 、 Cell culture 、 Irradiation 、 Immunology 、 Radiation therapy 、 Ionizing radiation 、 Cell killing
摘要: Several new approaches to radiation therapy with radionuclides have been discussed. Iron 55 is selectively utilized in the red cell developmental cycle and therapeutic doses, can lower marrow circulating erythrocyte levels much smaller degrees of effect on other lines. A serious complication, noted animal studies, induction neoplasma, especially osteosarcoma. Selective irradiation nucleus possible 125 IUdR. This results highly efficient killing due concentrated region ionization. High concentrations densely ionizing malignant may also be accomplished 211 At. The use labeled liposomes an additional approach delivery intracellular irradiation. None these applicable for practical treatment human malignancy at present time. importance their value as models future development methods that provide selective target sites.