作者: P. K. Reardon , Jakob Seidlitz , Simon Vandekar , Siyuan Liu , Raihaan Patel
关键词: Neuroscience 、 Normative 、 Human brain 、 Variation (linguistics) 、 Brain size 、 Sensory system 、 Brain shape 、 Neuroimaging 、 Motor system
摘要: Brain size variation over primate evolution and human development is associated with shifts in the proportions of different brain regions. Individual can vary almost twofold among typically developing humans, but consequences this for organization remain poorly understood. Using vivo neuroimaging data from more than 3000 individuals, we find that larger brains show greater areal expansion distributed frontoparietal cortical networks related subcortical regions limbic, sensory, motor systems. This redistribution recapitulates remodeling across evolution, manifests by early childhood linked to multiple markers heightened metabolic cost neuronal connectivity. Thus, shape systematically coupled naturally occurring variations through a scaling map integrates spatiotemporally diverse aspects neurobiology.