Predictive modeling for cancer drug discovery using canine models.
作者： Michael D. Lucroy , Mark A. Suckow
DOI: 10.1080/17460441.2020.1739644
关键词: Cancer drug discovery 、 Bioinformatics 、 Cancer 、 Disease 、 Animal model 、 Medicine
摘要: Rodent models of cancer lack many features associated with the disease in humans. Because dogs closely share an environment humans, as well comparable pathophysiology cancer, they repres...
sci-hub.se 参考文章(83)
Sedlacek Hh, Seiler Fr, Spontaneous mammary tumors in mongrel dogs. A relevant model to demonstrate tumor therapeutical success by application of neuraminidase-treated tumor cells. Developments in biological standardization. ,vol. 38, pp. 399- 412 ,(1977)
Carlos O. Rodriguez, Using canine osteosarcoma as a model to assess efficacy of novel therapies: can old dogs teach us new tricks? Advances in Experimental Medicine and Biology. ,vol. 804, pp. 237- 256 ,(2014) , 10.1007/978-3-319-04843-7_13
Goldschmidt Mh, Glickman Lt, McKee Lj, Prymak C, Epidemiologic, clinical, pathologic, and prognostic characteristics of splenic hemangiosarcoma and splenic hematoma in dogs: 217 cases (1985). Javma-journal of The American Veterinary Medical Association. ,vol. 193, pp. 706- 712 ,(1988)
Mark A. Suckow, Morris Pollard, Dietary prevention of hormone refractory prostate cancer in Lobund-Wistar rats: a review of studies in a relevant animal model. Comparative Medicine. ,vol. 56, pp. 461- 467 ,(2006)
Hiroyuki Mochizuki, Katherine Kennedy, Susan G. Shapiro, Matthew Breen, BRAF Mutations in Canine Cancers PLOS ONE. ,vol. 10, pp. e0129534- ,(2015) , 10.1371/JOURNAL.PONE.0129534
Heather L. Gardner, Joelle M. Fenger, Cheryl A. London, Dogs as a Model for Cancer Annual Review of Animal Biosciences. ,vol. 4, pp. 199- 222 ,(2016) , 10.1146/ANNUREV-ANIMAL-022114-110911
Kristin M. Wendelburg, Lori Lyn Price, Kristine E. Burgess, Jeremiah A. Lyons, Felicia H. Lew, John Berg, Survival time of dogs with splenic hemangiosarcoma treated by splenectomy with or without adjuvant chemotherapy: 208 cases (2001-2012). Javma-journal of The American Veterinary Medical Association. ,vol. 247, pp. 393- 403 ,(2015) , 10.2460/JAVMA.247.4.393
Deepika Dhawan, Melissa Paoloni, Shweta Shukradas, Dipanwita Roy Choudhury, Bruce A. Craig, José A. Ramos-Vara, Noah Hahn, Patty L. Bonney, Chand Khanna, Deborah W. Knapp, Comparative Gene Expression Analyses Identify Luminal and Basal Subtypes of Canine Invasive Urothelial Carcinoma That Mimic Patterns in Human Invasive Bladder Cancer PLOS ONE. ,vol. 10, pp. e0136688- ,(2015) , 10.1371/JOURNAL.PONE.0136688
John Arrowsmith, Phase III and submission failures: 2007–2010 Nature Reviews Drug Discovery. ,vol. 10, pp. 87- 87 ,(2011) , 10.1038/NRD3375
William A. Priester, Multiple primary tumors in domestic animals.A preliminary view with particular emphasis on tumors in dogs Cancer. ,vol. 40, pp. 1845- 1848 ,(1977) , 10.1002/1097-0142(197710)40:4+<1845::AID-CNCR2820400812>3.0.CO;2-8