Plasticity in smooth muscle, a hypothesis

摘要: The controversial finding that the thick filaments of smooth muscle can be evanescent leads to hypothesis large functional range this is accommodated by plastic rearrangements place more in series at longer lengths. Our preliminary shortening velocity and compliance dog tracheal were strongly dependent on adapted length, while force was much less length dependent, supports (V.R. Pratusevich, C.Y. Seow, L.E. Ford. Biophys. J. 66: A139, 1994). two further corollaries. first lengthening must accompany their reformation will cause a parallel transition: fewer long span but have cross bridges acting parallel. second there than one activating mechanism muscle. It known myosin light chain phosphorylation activates actomyosin ATPase, this...