Micropuncture studies on the filtration rate of single superficial and juxtamedullary glomeruli in the rat kidney.
作者： M. Horster , K. Thurau
DOI: 10.1007/BF00362733
关键词: Juxtamedullary Nephron 、 Kidney Concentrating Ability 、 Natriuresis 、 Sodium 、 Nephron 、 Chemistry 、 Low sodium 、 Renal function 、 Internal medicine 、 Kidney 、 Endocrinology
摘要: Single nephron filtration rates of superficial and juxtamedullary nephrons were determined in high low sodium rats. GFR was calculated from TF/P inulin tubular flow rate single corresponding data long loops Henle. In rats 23.5±6.4 (SD)×10−6 ml/min×g KW, 58.2±13.6 total kidney (C In) 0.94±0.16 KW. Using these values, a number 30,000 glomeruli per kidney, the to be 23,267 6,733, respectively. During diet increased 38.1±11.3 decreased 16.5±6.6, increasing 1.01±0.24. Calculation again revealed same distribution two types. End-proximal 2.36±0.36 2.31±0.28 Loops Henle intratubular inversely related: highest values lowest found descending limb. These quantify on functional basis suggest mechanism by which adjusts excretion altering contribution each type GFR.
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