Excessive apoptosis and ROS induced by ethionine affect neural cell viability and differentiation

作者: Li Zhang , Dandan Li , Juan Zhang , Ping Yan , Xueqin Liu

DOI: 10.1093/ABBS/GMAA093

关键词: Cell biologyNeural tubeApoptosisCyclin D1Neural stem cellViability assayCell cultureBiologyEthionineCell

摘要: … reduced significantly, as the average percentage of map2-positive neurons and GFAP-positive … Flow cytometry analysis results showed a significant increase in ROS mean fluorescence …

参考文章(41)
Melvin. Levine, Harold. Tarver, Studies on ethionine. III. Incorporation of ethionine into rat proteins. Journal of Biological Chemistry. ,vol. 192, pp. 835- 850 ,(1951) , 10.1016/S0021-9258(19)77806-5
Hai-yang Wang, Ren-ping Huang, Peng Han, Dong-bo Xue, Hai-bin Li, Bing Liu, Peng Shan, Qing-shan Wang, Ke-shen Li, Ha-li Li, The effects of artemisinin on the proliferation and apoptosis of vascular smooth muscle cells of rats Cell Biochemistry and Function. ,vol. 32, pp. 201- 208 ,(2014) , 10.1002/CBF.2995
Chiara Rolando, Verdon Taylor, Neural Stem Cell of the Hippocampus Current Topics in Developmental Biology. ,vol. 107, pp. 183- 206 ,(2014) , 10.1016/B978-0-12-416022-4.00007-X
Fatemah Chehrehasa, Adrian C.B. Meedeniya, Patrick Dwyer, Greger Abrahamsen, Alan Mackay-Sim, EdU, a new thymidine analogue for labelling proliferating cells in the nervous system. Journal of Neuroscience Methods. ,vol. 177, pp. 122- 130 ,(2009) , 10.1016/J.JNEUMETH.2008.10.006
Louisa P.E. Dunlevy, Katie A. Burren, Kevin Mills, Lyn S. Chitty, Andrew J. Copp, Nicholas D.E. Greene, Integrity of the methylation cycle is essential for mammalian neural tube closure Birth Defects Research Part A-clinical and Molecular Teratology. ,vol. 76, pp. 544- 552 ,(2006) , 10.1002/BDRA.20286
Shuhei Ishii, Miku Hirane, Sayumi Kato, Nobuyuki Fukushima, Toshifumi Tsujiuchi, Opposite effects of GPR120 and GPR40 on cell motile activity induced by ethionine in liver epithelial cells. Biochemical and Biophysical Research Communications. ,vol. 456, pp. 135- 138 ,(2015) , 10.1016/J.BBRC.2014.11.047
Pei-Feng Li, Rainer Dietz, Rüdiger von Harsdorf, Reactive oxygen species induce apoptosis of vascular smooth muscle cell FEBS Letters. ,vol. 404, pp. 249- 252 ,(1997) , 10.1016/S0014-5793(97)00093-8
Jose Gomez, Ines Sanchez-Roman, Alexia Gomez, Carlota Sanchez, Henar Suarez, Monica Lopez-Torres, Gustavo Barja, Methionine and homocysteine modulate the rate of ROS generation of isolated mitochondria in vitro Journal of Bioenergetics and Biomembranes. ,vol. 43, pp. 377- 386 ,(2011) , 10.1007/S10863-011-9368-1