Coronary heart disease and drinking water. A search in two Finnish male cohorts for epidemiologic evidence of a water factor.

摘要: Abstract A search for the hypothetical factor in drinking water that might influence mortality from C.H.D. was made two rural areas western and eastern Finland. 10-yr follow-up of resident males had shown a higher death rate area. The difference is only partly explained by currently known risk factors levels 22 characteristics were investigated 327 wells six tap-water samples. In both used soft but mean concentrations several components differ. general, are lower significant pH, F, Ca, Mg, Na, Cr. NO3, K, Cu, Co, Ni, Ba significantly populations there indications from, or development of, connected with quality water, particularly low constituents. Assuming single constituent responsible between cohorts, elements most suspect chromium and, to lesser degree, copper. associated high copper water. Findings on magnesium equivocal, no association observed calcium. relationships following also investigated: systolic blood pressure, serum cholesterol, extrasystoles ECG, cigarette smoking. area concentration cholesterol correlated negatively