Prevalence, predictors, and outcomes of patients with non-ST-segment elevation myocardial infarction and insignificant coronary artery disease: results from the Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC/AHA Guidelines (CRUSADE) initiative.
作者： Manesh R. Patel , Anita Y. Chen , Eric D. Peterson , L. Kristin Newby , Charles V. Pollack
DOI: 10.1016/J.AHJ.2006.02.035
关键词: Odds ratio 、 Cardiology 、 Medicine 、 Coronary artery disease 、 Cardiac catheterization 、 ST elevation 、 Internal medicine 、 Population 、 Risk factor 、 Myocardial infarction 、 Unstable angina
摘要: Background Unlike ST-segment elevation myocardial infarction, the degree of stenosis and physiology ischemia varies in patients with non–ST-segment infarction (NSTEMI). The prevalence, predictors, outcomes NSTEMI who lack significant epicardial coronary artery disease (CAD) routine clinical practice remain poorly characterized. We sought to determine insignificant CAD. Methods analyzed 38301 CRUSADE quality improvement initiative underwent cardiac catheterization prevalence factors associated CAD (all stenoses Results A total 3306 (8.6%) had strongest multivariable predictors were female sex (odds ratio 2.8, 95% CI 2.6-3.1), younger age per 10-year decrease 1.5, 1.5-1.6), current/recent smoking 1.9, 1.7-2.0). Inhospital rates death 0.65% for compared 2.36% ( P Conclusion Insignificant is present 9% a low incidence adverse outcomes. are age. These findings underscore need research understand pathophysiology this population.
elsevier.com
sci-hub.se 参考文章(26)
Elliott M Antman, Troponin measurements in ischemic heart disease: more than just a black and white picture∗∗Editorials published in the Journal of the American College of Cardiologyreflect the views of the authors and do not necessarily represent the views of JACCor the American College of Cardiology. Journal of the American College of Cardiology. ,vol. 38, pp. 987- 990 ,(2001) , 10.1016/S0735-1097(01)01497-8
Taro Saito, Haruhiko Date, Izumi Taniguchi, Shouta Nakamura, Hideki Oka, Yuji Mizuno, Katsuo Noda, Seishi Yamashita, Shuichi Oshima, Hirofumi Yasue, Angiographic evaluation of culprit lesions in acute coronary syndrome : Relation to the original site on previous coronary angiography Japanese Circulation Journal-english Edition. ,vol. 62, pp. 359- 363 ,(1998) , 10.1253/JCJ.62.359
Michael C Kontos, Rakesh Shah, Lucie M Fritz, F.Philip Anderson, James L Tatum, Joseph P Ornato, Robert L Jesse, Implication of different cardiac troponin I levels for clinical outcomes and prognosis of acute chest pain patients. Journal of the American College of Cardiology. ,vol. 43, pp. 958- 965 ,(2004) , 10.1016/J.JACC.2003.10.036
Matthew T. Roe, Robert A. Harrington, Danielle M. Prosper, Karen S. Pieper, Deepak L. Bhatt, A. Michael Lincoff, Maarten L. Simoons, Martijn Akkerhuis, E. Magnus Ohman, Michael M. Kitt, Alec Vahanian, Witold Ruzyllo, Karl Karsch, Robert M. Califf, Eric J. Topol, Clinical and Therapeutic Profile of Patients Presenting With Acute Coronary Syndromes Who Do Not Have Significant Coronary Artery Disease Circulation. ,vol. 102, pp. 1101- 1106 ,(2000) , 10.1161/01.CIR.102.10.1101
Michael J. Pecora, Gary S. Roubin, B.Woodfin Cobbs, Stephen G. Ellis, William S. Weintraub, Spencer B. King, Presentation and late outcome of myocardial infarction in the absence of angiographically significant coronary artery disease American Journal of Cardiology. ,vol. 62, pp. 363- 367 ,(1988) , 10.1016/0002-9149(88)90959-9
Michael C Kontos, Lucie M Fritz, F.Philip Anderson, James L Tatum, Joseph P Ornato, Robert L Jesse, Impact of the troponin standard on the prevalence of acute myocardial infarction American Heart Journal. ,vol. 146, pp. 446- 452 ,(2003) , 10.1016/S0002-8703(03)00245-X
Daniel J Diver, Jonathan D Bier, Paula E Ferreira, Barry L Sharaf, Carolyn McCabe, Bruce Thompson, Bernard Chaitman, David O Williams, Braunwald Eugene, TIMI-IIIA Investigators, None, Clinical and arteriographic characterization of patients with unstable angina without critical coronary arterial narrowing (from the TIMI-IIIA trial) American Journal of Cardiology. ,vol. 74, pp. 531- 537 ,(1994) , 10.1016/0002-9149(94)90739-0
Chao-Hung Wang, Li-Tang Kuo, Ming-Jui Hung, Wen-Jin Cherng, Coronary vasospasm as a possible cause of elevated cardiac troponin I in patients with acute coronary syndrome and insignificant coronary artery disease. American Heart Journal. ,vol. 144, pp. 275- 281 ,(2002) , 10.1067/MHJ.2002.123843
Harvey D. White, Things ain't what they used to be: Impact of a new definition of myocardial infarction American Heart Journal. ,vol. 144, pp. 933- 937 ,(2002) , 10.1067/MHJ.2002.129780
M PANTEGHINI, Role and importance of biochemical markers in clinical cardiology European Heart Journal. ,vol. 25, pp. 1187- 1196 ,(2004) , 10.1016/J.EHJ.2004.04.026