Fabrication and mechanical properties of PLLA and CPC composite scaffolds

作者: Shanglong Xu , Wei Guo , Junjun Lu , Wei Li

DOI: 10.1007/S12206-012-0732-9

关键词: BrittlenessFabricationScaffoldModulusBone fixationComposite materialCompoundingCompressive strengthMaterials scienceComposite number

摘要: The brittleness and insufficient strength of biomaterials such as calcium phosphate cement (CPC) limit their applications in physiologically non-load-bearing bone lesions. These limitations stimulated the research for developing degradable polymer-ceramic composite materials that can closely match modulus bones. In this study, poly (L-lactic acid)/calcium (PLLA/CPC) scaffolds were fabricated via a four-step process, namely, measurement, prototyping, compounding, dissolving. design mechanical properties PLLA/CPC structures theoretically experimentally studied. scaffold improved CPC. CPC’s compressive strengthening percentage increase with higher PLLA volume. Such composites may have clinical use load-bearing fixation.

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