作者: Gabriele V. Ronnett , Jeffrey S. Nye , Solomon H. Snyder , Lynda D. Hester
DOI:
关键词: Screening method 、 Glial fibrillary acidic protein 、 Cell biology 、 Nerve growth factor 、 Biochemistry 、 Neurofilament 、 Stain 、 Cell culture 、 Biology
摘要: This invention is directed to continuous, non-maligant, neuronal cell lines, the cells of which: a) in undifferentiated form are essentially free branched process; b) stain positively for neurofilament protein and neurotransmitters; c) do not glial fibrillary acidic protein; d) presence nerve growth factor differentiate into with long processes. Derivative lines such also contemplated. The useful screening methods evaluation chemical biological compounds as well therapeutic uses.