2'-epi-2'-O-Acetylthevetin B extracted from seeds of Cerbera manghas L. induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells.

作者: Bo Feng , Yue-Wei Guo , Cai-Guo Huang , Liang Li , Ruo-Hua Chen

DOI: 10.1016/J.CBI.2009.10.012

关键词: Cell cycle checkpointCaspaseMembrane potentialReactive oxygen speciesHepatocellular carcinomaCytotoxicityBiologyCerbera manghasApoptosisMolecular biology

摘要: 2� -epi-2 � -O-Acetylthevetin B (GHSC-74) Cell cycle arrest Mitochondrial membrane potential (�� m) Apoptosis-inducing factor (AIF) Reactive oxygen species (ROS) Caspase Apoptosis

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