Essential roles of Akt/Snail pathway in microcystin-LR-induced tight junction toxicity in Sertoli cell.
作者： Yuan Zhou , Xiao Geng , Yu Chen , Hao Shi , Yan Yang
DOI: 10.1016/J.FCT.2018.01.004
关键词: Claudin 、 Cell biology 、 Snail 、 Protein phosphatase 2 、 Signal transduction 、 Occludin 、 Tight junction 、 Protein kinase B 、 Sertoli cell 、 Chemistry
摘要: … In the present study, our results indicated that MC-LR up-regulated the expression of Snail in the protein and mRNA levels, which is consistent with previous results showing that …
sci-hub.se 参考文章(57)
Yuan Zhou, Hui Wang, Cong Wang, Xuefeng Qiu, Mikael Benson, Xiaoqin Yin, Zou Xiang, Dongmei Li, Xiaodong Han, Roles of miRNAs in microcystin-LR-induced Sertoli cell toxicity. Toxicology and Applied Pharmacology. ,vol. 287, pp. 1- 8 ,(2015) , 10.1016/J.TAAP.2015.05.008
Chunjin Li, Wanhong Li, Shuxiong Chen, Zhichen Kang, Lina Sun, Hongjiao Li, Lu Chen, Jiahui Rao, Yun Zhao, Jiaxin Yu, Xu Zhou, 4-Methylcatechol-induced cell damage in TM4 Sertoli cells. Cell Biology International. ,vol. 39, pp. 770- 774 ,(2015) , 10.1002/CBIN.10420
Chengmin Wang, Wenjuan Fu, Chao Quan, Maosheng Yan, Changjiang Liu, Suqin Qi, Kedi Yang, The role of Pten/Akt signaling pathway involved in BPA-induced apoptosis of rat Sertoli cells. Environmental Toxicology. ,vol. 30, pp. 793- 802 ,(2015) , 10.1002/TOX.21958
Kay A. Mereish, Rikki Solow, Effect of antihepatotoxic agents against microcystin-LR toxicity in cultured rat hepatocytes. Pharmaceutical Research. ,vol. 7, pp. 256- 261 ,(1990) , 10.1023/A:1015822028414
Thomas C. Nardelli, Hanno C. Erythropel, Bernard Robaire, Toxicogenomic Screening of Replacements for Di(2-Ethylhexyl) Phthalate (DEHP) Using the Immortalized TM4 Sertoli Cell Line PLOS ONE. ,vol. 10, pp. e0138421- ,(2015) , 10.1371/JOURNAL.PONE.0138421
Liang Chen, Jun Chen, Xuezhen Zhang, Ping Xie, A review of reproductive toxicity of microcystins Journal of Hazardous Materials. ,vol. 301, pp. 381- 399 ,(2016) , 10.1016/J.JHAZMAT.2015.08.041
Yu Chen, Yuan Zhou, Xueting Wang, Weiping Qian, Xiaodong Han, Microcystin-LR induces autophagy and apoptosis in rat Sertoli cells in vitro Toxicon. ,vol. 76, pp. 84- 93 ,(2013) , 10.1016/J.TOXICON.2013.09.005
Ricardo Assunção, Mariana Ferreira, Carla Martins, Irene Diaz, Beatriz Padilla, Didier Dupont, Mauro Bragança, Paula Alvito, Applicability of In Vitro Methods to Study Patulin Bioaccessibility and Its Effects on Intestinal Membrane Integrity Journal of Toxicology and Environmental Health. ,vol. 77, pp. 983- 992 ,(2014) , 10.1080/15287394.2014.911138
Céline Fiorini, Anne Tilloy-Ellul, Stephan Chevalier, Claude Charuel, Georges Pointis, Sertoli cell junctional proteins as early targets for different classes of reproductive toxicants Reproductive Toxicology. ,vol. 18, pp. 413- 421 ,(2004) , 10.1016/J.REPROTOX.2004.01.002
Alexandre Campos, Vitor Vasconcelos, Molecular Mechanisms of Microcystin Toxicity in Animal Cells International Journal of Molecular Sciences. ,vol. 11, pp. 268- 287 ,(2010) , 10.3390/IJMS11010268