Reduction of Dietary Acid Load as a Potential Countermeasure for Bone Loss Associated with Spaceflight

摘要: In several studies we tested the concepts that diet can alter acid-base balance and reducing dietary acid load has a positive effect on maintenance of bone. study 1, (n = 11, 60-90 d bed rest), renal was estimated from its chemical composition, positively correlated with urinary markers bone resorption (P less than 0.05); is, greater load, excretion markers. 2, in males 8, 30 an estimate ratio nonvolatile precursors to base 0.05) resorption. 3, for 28 subjects received either placebo 6) or essential amino supplement 7) included methionine, known precursor. During rest (28 d), calcium baseline levels supplemented group but not control 0.05), group, pH decreased 0.05). 4, occurred space crew members who potassium citrate during spaceflight 4-6 months were 8) Reducing potential mitigate increased spaceflight, may serve as loss countermeasure.