Prognostic Significance of Osteopontin Expression in Human Gastric Carcinoma

作者: Motoshige Higashiyama , Tetsuo Ito , Eiji Tanaka , Yutaka Shimada

DOI: 10.1245/S10434-007-9564-8

关键词: Clinical significanceSurvival rateMedicineGastric carcinomaSurgical oncologyHuman gastric carcinomaOsteopontinRegulation of gene expressionPathologyBlot

摘要: Background Osteopontin (OPN) is a secreted, integrin-binding glycophosphoprotein that has been implicated in the progression of various solid tumors. To evaluate clinical significance OPN gastric carcinoma, we investigated expression resected

参考文章(30)
Rudland Ps, Barraclough R, Oates Aj, The role of osteopontin in tumorigenesis and metastasis. Invasion & Metastasis. ,vol. 17, pp. 1- 15 ,(1997)
S. Yamamoto, Y. Ushio, J.-I. Kuratsu, Y. Saitoh, H. Takeshima, Expression of osteopontin in human glioma. Its correlation with the malignancy. Laboratory Investigation. ,vol. 72, pp. 55- 63 ,(1995)
David T. Denhardt, Ann F. Chambers, Sylvia M. Wilson, Ann Marie Craig, Elke I. Behrend, Reduced Malignancy of ras-transformed NIH 3T3 Cells Expressing Antisense Osteopontin RNA Cancer Research. ,vol. 54, pp. 832- 837 ,(1994)
David R. Cox, Regression Models and Life-Tables Springer Series in Statistics. ,vol. 34, pp. 527- 541 ,(1992) , 10.1007/978-1-4612-4380-9_37
Lynn M. Matrisian, Howard C. Crawford, Lucy Liaw, Lucy Liaw, Distinct roles of osteopontin in host defense activity and tumor survival during squamous cell carcinoma progression in vivo Cancer Research. ,vol. 58, pp. 5206- 5215 ,(1998)
Shiva S Forootan, Christopher S Foster, Vijay R Aachi, Janet Adamson, Paul H Smith, Ke Lin, Youqiang Ke, None, Prognostic significance of osteopontin expression in human prostate cancer International Journal of Cancer. ,vol. 118, pp. 2255- 2261 ,(2006) , 10.1002/IJC.21619
Hung-Wei Pan, Yueh-Hsing Ou, Shian-Yang Peng, Shu-Hsian Liu, Po-Lin Lai, Po-Hwaung Lee, Jin-Chuan Sheu, Chi-Ling Chen, Hey-Chi Hsu, Overexpression of osteopontin is associated with intrahepatic metastasis, early recurrence, and poorer prognosis of surgically resected hepatocellular carcinoma. Cancer. ,vol. 98, pp. 119- 127 ,(2003) , 10.1002/CNCR.11487
Donald R. Senger, Dyann F. Wirth, Richard O. Hynes, Transformed mammalian cells secrete specific proteins and phosphoproteins Cell. ,vol. 16, pp. 885- 893 ,(1979) , 10.1016/0092-8674(79)90103-X
Teruyoshi Ue, Hiroshi Yokozaki, Yasuhiko Kitadai, Soichiro Yamamoto, Wataru Yasui, Takenori Ishikawa, Eiichi Tahara, Co‐expression of osteopontin and CD44v9 in gastric cancer International Journal of Cancer. ,vol. 79, pp. 127- 132 ,(1998) , 10.1002/(SICI)1097-0215(19980417)79:2<127::AID-IJC5>3.0.CO;2-V
Ani C. Khodavirdi, Zhigang Song, Shangxin Yang, Chen Zhong, Shunyou Wang, Hong Wu, Colin Pritchard, Peter S. Nelson, Pradip Roy-Burman, Increased Expression of Osteopontin Contributes to the Progression of Prostate Cancer Cancer Research. ,vol. 66, pp. 883- 888 ,(2006) , 10.1158/0008-5472.CAN-05-2816