Nicotinamide Phosphoribosyl Transferase Controls NLRP3 Inflammasome Activity Through MAPK and NF-κB Signaling in Nucleus Pulposus Cells, as Suppressed by Melatonin
作者： Yingjie Huang , Yan Peng , Jianchao Sun , Shuangxing Li , Junmin Hong
DOI: 10.1007/S10753-019-01166-Z
关键词: Tumor necrosis factor alpha 、 Western blot 、 Chemistry 、 Matrix (biology) 、 Melatonin 、 Gene knockdown 、 MAPK/ERK pathway 、 Downregulation and upregulation 、 Cell biology 、 Inflammasome
摘要: … in NP cells via autophagy [17], we further clarify the effect of NAMPT inhibition on autophagy in the … As reported by our group before [26], TNF-α has no effect on autophagy of NP cells. …
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