Association between Weight Change during Treatment and Treatment Outcome in Patients with Smear Positive Pulmonary Tuberculosis

摘要: Tuberculosis (TB) is known as a disease of poverty and declared a global public health emergency by World Health Organization (WHO). Pulmonary tuberculosis the most common type TB wasting disease. It is expected that patients who lost weight during course disease, will gain successful treatment. So aim this study was to assess the body changes through treatment its possible association with treatment outcome in Nishapur, an ancient city Razavi Khorasan province Iran. This observational analytical study. Patients were selected according inclusion exclusion criteria available information. Treatment Protocol for all Directly Observed Treatment, short Course Strategy (at least 6 months). All were weighed at beginning treatment, after two months at end Outcome of classified into: cured, completed failure and death. Then impact compared in subgroups. From 874 patients, 819 (93.9%) new cases, 48 (5.3%) relapse, 5 (0.6%) did not complete their 2 (0.2%) had failed prior therapy. The symptoms were: cough, sputum, loss, fever, sweats, hemoptysis. 8.1% had radiologic signs cavity (2.9%). weight change 2.91 ± 5.59 kg cured group, 3.3 3.29 in completed 2.95 failure group 1.02 ± 3.27 dead respectively. These differences statistically significant between four groups (p