作者: Arni SR Srinivasa Rao , Maggie H Chen , Ba' Z Pham , Andrea C Tricco , Vladimir Gilca
关键词: Demography 、 Incidence (epidemiology) 、 Immunology 、 Cohort study 、 Cohort effect 、 Medical microbiology 、 Hepatitis A vaccine 、 Vaccination 、 Hepatitis A 、 Medicine 、 Seroprevalence
摘要: Background Infection rates for many infectious diseases have declined over the past century. This has created a cohort effect, whereby older individuals experienced higher infection rate in their than younger do now. As result, age-stratified seroprevalence profiles often differ from what would be expected constant rates.