Cohort effects in dynamic models and their impact on vaccination programmes: an example from Hepatitis A

作者: Arni SR Srinivasa Rao , Maggie H Chen , Ba' Z Pham , Andrea C Tricco , Vladimir Gilca

DOI: 10.1186/1471-2334-6-174

关键词: DemographyIncidence (epidemiology)ImmunologyCohort studyCohort effectMedical microbiologyHepatitis A vaccineVaccinationHepatitis AMedicineSeroprevalence

摘要: Background Infection rates for many infectious diseases have declined over the past century. This has created a cohort effect, whereby older individuals experienced higher infection rate in their than younger do now. As result, age-stratified seroprevalence profiles often differ from what would be expected constant rates.

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