The SUV39H1 inhibitor chaetocin induces differentiation and shows synergistic cytotoxicity with other epigenetic drugs in acute myeloid leukemia cells
作者： Y-S Lai , J-Y Chen , H-J Tsai , T-Y Chen , W-C Hung
DOI: 10.1038/BCJ.2015.37
关键词: Myeloid leukemia 、 Biology 、 Leukemia 、 U937 cell 、 Cellular differentiation 、 Cytotoxicity 、 Bromodomain 、 Histone H3 、 Cancer research 、 Histone deacetylase inhibitor
摘要: … is generally found in AML cells and is associated with blockage … and cytotoxic effect of G9a and SUV39H1 inhibitor in AML cell lines … of AML cells and shows synergistic cytotoxicity when …
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