A rhodamine based fluorescent probe for Hg2+ and its application to cellular imaging.
作者： Fanyong Yan , Donglei Cao , Ning Yang , Meng Wang , Linfeng Dai
DOI: 10.1016/J.SAA.2012.12.079
关键词: Fluorescent imaging 、 Fluorescence 、 Cellular imaging 、 Rhodamine 、 Chemistry 、 Selectivity 、 Photochemistry 、 Detection limit 、 Ion 、 Metal
摘要: Abstract A new rhodamine-based fluorescent probe (Rh-F) for detection of Hg2+ ions was synthesized, which could bind in aqueous ethanol (7:3, v/v) at pH 7.0 with detectable change color and fluorescence. The response is based on a ring opening reaction formation 1:1 complex, while ring-opening process spirolactam enables large enhancement colorimetric upon the addition Hg2+. reversible linear range between 200 nM 1000 nM, limit 4.2 nM. Selectivity competition experiments various other metal ion revealed that Rh-F possesses highly selective to Furthermore, successfully applied imaging L-929 cells confirm can be used as monitoring living cells.
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