VEGF and colon cancer growth beyond angiogenesis: does VEGF directly mediate colon cancer growth via a non-angiogenic mechanism?

作者: Amrita Ahluwalia , Michael Jones , Tamara Matysiak-Budnik , Andrzej Tarnawski

DOI: 10.2174/1381612819999131218175905

关键词: Vascular endothelial growth factor ANeovascularizationAngiogenesisHIF1AMedicineVascular endothelial growth factorCancerInternal medicineBevacizumabColorectal cancerOncology

摘要: … metastatic colon cancer. However, the source of VEGF in colon cancer tissue, the mechanisms of VEGF … human colon cancer cells to decrease expression of HIF-1 and VEGF as well as …

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