Structure and properties of clinical coralline implants measured via 3D imaging and analysis

摘要: The development and design of advanced porous materials for biomedical applications requires a thorough understanding how material structure impacts on mechanical transport properties. This paper illustrates 3D imaging analysis study two clinically proven coral bone graft samples (Porites Goniopora). Images are obtained from X-ray micro-computed tomography (micro-CT) at resolution 16.8 microm. A visual comparison the images shows very different structure; Porites has homogeneous consistent pore size while Goniopora bimodal strongly disordered structure. number structural characteristics measured directly including volume-to-surface-area, solid distributions, chord length measurements tortuosity. Computational results made digitized tomographic presented permeability, diffusivity elastic modulus samples. allow one to quantify differences between digital can provide more assessment biomaterial wall thickness, local flow, properties diffusion pathways. We discuss implications these optimal scaffold tissue ingrowth.