Omics of Blood Pressure and Hypertension

作者: Donna K. Arnett , Steven A. Claas

DOI: 10.1161/CIRCRESAHA.118.311342

关键词: MetabolomicsBlood pressureEssential hypertensionProteomicsBiologyComputational biologyGenomicsPathophysiology of hypertensionEpigenomicsGenetic architecture

摘要: … This review provides a broad survey of the omics of BP and hypertension, including genomics, transcriptomics, proteomics, metabolomics, and multiomic methods. The discussion of …

参考文章(76)
Melina Claussnitzer, Simon N. Dankel, Kyoung-Han Kim, Gerald Quon, Wouter Meuleman, Christine Haugen, Viktoria Glunk, Isabel S. Sousa, Jacqueline L. Beaudry, Vijitha Puviindran, Nezar A. Abdennur, Jannel Liu, Per-Arne Svensson, Yi-Hsiang Hsu, Daniel J. Drucker, Gunnar Mellgren, Chi-Chung Hui, Hans Hauner, Manolis Kellis, FTO Obesity Variant Circuitry and Adipocyte Browning in Humans The New England Journal of Medicine. ,vol. 373, pp. 895- 907 ,(2015) , 10.1056/NEJMOA1502214
Massimo Mangino, Marina Cecelja, Cristina Menni, Pei-Chien Tsai, Wei Yuan, Kerrin Small, Jordana Bell, Gary F Mitchell, Phillip Chowienczyk, Tim D Spector, AortaGen Consortium, Integrated multiomics approach identifies calcium and integrin-binding protein-2 as a novel gene for pulse wave velocity Journal of Hypertension. ,vol. 34, pp. 79- 87 ,(2016) , 10.1097/HJH.0000000000000732
Merry L. Lindsey, Manuel Mayr, Aldrin V. Gomes, Christian Delles, D. Kent Arrell, Anne M. Murphy, Richard A. Lange, Catherine E. Costello, Yu-Fang Jin, Daniel T. Laskowitz, Flora Sam, Andre Terzic, Jennifer Van Eyk, Pothur R. Srinivas, Transformative Impact of Proteomics on Cardiovascular Health and Disease: A Scientific Statement From the American Heart Association. Circulation. ,vol. 132, pp. 852- 872 ,(2015) , 10.1161/CIR.0000000000000226
W ZHAO, G CHASE, W LIU, Genome scan meta-analysis for hypertension. American Journal of Hypertension. ,vol. 17, pp. 1100- 1106 ,(2004) , 10.1016/J.AMJHYPER.2004.07.014
Cynthia A. van Deventer, Jeremie Z. Lindeque, Peet J. Jansen van Rensburg, Leoné Malan, Francois H. van der Westhuizen, Roan Louw, Use of metabolomics to elucidate the metabolic perturbation associated with hypertension in a black South African male cohort: the SABPA study. Journal of The American Society of Hypertension. ,vol. 9, pp. 104- 114 ,(2015) , 10.1016/J.JASH.2014.11.007
Xiaogang Wu, Mohammad Al Hasan, Jake Yue Chen, Pathway and Network Analysis in Proteomics Journal of Theoretical Biology. ,vol. 362, pp. 44- 52 ,(2014) , 10.1016/J.JTBI.2014.05.031
Julia Krushkal, Momiao Xiong, Robert Ferrell, Charles F Sing, Stephen T Turner, Eric Boerwinkle, Linkage and Association of Adrenergic and Dopamine Receptor Genes in the Distal Portion of the Long Arm of Chromosome 5 With Systolic Blood Pressure Variation Human Molecular Genetics. ,vol. 7, pp. 1379- 1383 ,(1998) , 10.1093/HMG/7.9.1379
Gilbert S Omenn, David J States, Marcin Adamski, Thomas W Blackwell, Rajasree Menon, Henning Hermjakob, Rolf Apweiler, Brian B Haab, Richard J Simpson, James S Eddes, Eugene A Kapp, Robert L Moritz, Daniel W Chan, Alex J Rai, Arie Admon, Ruedi Aebersold, Jimmy Eng, William S Hancock, Stanley A Hefta, Helmut Meyer, Young‐Ki Paik, Jong‐Shin Yoo, Peipei Ping, Joel Pounds, Joshua Adkins, Xiaohong Qian, Rong Wang, Valerie Wasinger, Chi Yue Wu, Xiaohang Zhao, Rong Zeng, Alexander Archakov, Akira Tsugita, Ilan Beer, Akhilesh Pandey, Michael Pisano, Philip Andrews, Harald Tammen, David W Speicher, Samir M Hanash, None, Overview of the HUPO Plasma Proteome Project: results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly-available database. Proteomics. ,vol. 5, pp. 3226- 3245 ,(2005) , 10.1002/PMIC.200500358
Richard P. Lifton, Robert G. Dluhy, Michael Powers, Glenn M. Rich, Sandra Cook, Stanley Ulick, Jean-Marc Lalouel, A chimaeric 11 beta-hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension. Nature. ,vol. 355, pp. 262- 265 ,(1992) , 10.1038/355262A0
Teri A Manolio, Francis S Collins, Nancy J Cox, David B Goldstein, Lucia A Hindorff, David J Hunter, Mark I McCarthy, Erin M Ramos, Lon R Cardon, Aravinda Chakravarti, Judy H Cho, Alan E Guttmacher, Augustine Kong, Leonid Kruglyak, Elaine Mardis, Charles N Rotimi, Montgomery Slatkin, David Valle, Alice S Whittemore, Michael Boehnke, Andrew G Clark, Evan E Eichler, Greg Gibson, Jonathan L Haines, Trudy FC Mackay, Steven A McCarroll, Peter M Visscher, None, Finding the missing heritability of complex diseases. Nature. ,vol. 461, pp. 747- 753 ,(2009) , 10.1038/NATURE08494