Development of Combination Therapy with Targeted Agents

摘要: With the rapid increase in available effective agents, there has been a push to advance outcomes combination approaches. landscape of agents with activity including cytokines, vascular endothelial growth factor (VEGF) pathway inhibitors, and mammalian target rapamycin (mTOR) most combinational approaches examined have included these agents. recent reports several important studies, our vision therapy application is coming into focus. Although some positive findings learned studies which could be expanded on, it apparent that identifying new novel mechanisms subsets patients who benefit from drugs are critically advancing