Prevention of Population Shifts in Oral Microbial Communities in vitro by Low Fluoride Concentrations

摘要: A continuous culture system has been used to study the effects of low (sub-MIC) levels sodium fluoride on stability and metabolism a defined oral microbial community. The microflora was also subjected glucose pulses at pH 7.0, with without subsequent control. At supply 1 mmol/L NaF reduced slightly viable counts microflora, although their proportions were relatively unaffected. during pulsing, prevented rise in A. viscosus B. intermedius. Glucose pulsing control absence markedly inhibited growth many species, L. casei, V. dispar, S. mutans predominated culture. Fluoride (1 mmol/L), either pulsed or provided continuously, both rate change degree fall pH, doing so enrichment pH-mediated inhibition ...