Pharmacokinetics and clinical efficacy of phenobarbital in asphyxiated newborns treated with hypothermia: a thermopharmacological approach.
作者： M. P. H. van den Broek , F. Groenendaal , M. C. Toet , H. L. M. van Straaten , J. G. C. van Hasselt
DOI: 10.1007/S40262-012-0004-Y
关键词: Medicine 、 Sedative 、 Phenobarbital 、 Pharmacokinetics 、 Pharmacology 、 Anesthesia 、 Clinical trial 、 Intensive care 、 Hypnotic 、 Anticonvulsant 、 Hypothermia
摘要: Background and Objectives Therapeutic hypothermia can influence the pharmacokinetics pharmacodynamics of drugs, discipline which is called thermopharmacology. We studied effect therapeutic on phenobarbital in asphyxiated neonates, clinical efficacy continuous amplitude-integrated electroencephalography (aEEG) a prospective study.
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