Determining the Role of Autophagy in HER2/neu-Induced Mammary Tumor Dormancy and Recurrence

作者: Samantha L. Dwyer

DOI:

关键词: Breast cancerBreast cancer recurrenceMammary tumorBiologyDormancyAutophagyTumor cellsCancer researchMetforminHER2/neuPathology

摘要: v LIST OF ILLUSTRATIONS viii CHAPTER I: Autophagy and Breast Cancer Recurrence 1 II: is Required for HER2/neu-Induced Mammary Tumor by Promoting the Survival of Dormant Cells 20 III: Additional Studies to Determine Effects Inhibiting on Dormancy 54 IV: Rapamycin Delays 77 V: Determining if Metformin Promotes 102 VI: Summary Future Directions 119 REFERENCES 148

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